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Instruments / Technical Area	Publication Details	Published	Actions
I08-Scanning X-ray Microscopy beamline (SXM)	Illuminating the brain: revealing brain biochemistry with synchrotron x-ray spectromicroscopy James Everett , Jake Brooks , Frederik Lermyte , Vindy Tjendana Tjhin , Ian Hands-Portman , Emily Hill , Joanna F. Collingwood , Neil D. Telling Journal Of Electron Spectroscopy And Related Phenomena 14 DOI: 10.1016/j.elspec.2023.147355 Diamond Proposal Number(s): [15230, 24534, 29042, 30776] Open Access Show Abstract ▼ Abstract: The synchrotron x-ray spectromicroscopy technique Scanning Transmission X-ray Microscopy (STXM) offers a powerful means to examine the underlying biochemistry of biological systems, owing to its combined chemical sensitivity and nanoscale spatial resolution. Here we introduce and demonstrate methodology for the use of STXM to examine the biochemistry of the human brain. We then discuss how this approach can help us better understand the biochemical changes that occur during the development of degenerative brain disorders, potentially facilitating the development of new therapies for disease diagnosis and treatment.	Jun 2023

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