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Multiple Lyotropic Polymorphism of a PEG-Peptide Diblock Copolymer in Aqueous Solution

DOI: 10.1002/adma.200800266 DOI Help

Authors: M.j Krysmann (University of Reading) , Valeria Castelletto (University of Reading) , Ian Hamley (Diamond Light Source)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Advanced Materials , VOL 20 (23) , PAGES 4394-4397

State: Published (Approved)
Published: January 2008

Abstract: Nematic and hexagonal columnar liquid crystal phase formation by a PEG-peptide conjugate is reported. The results are relevant to peptide-polymer Conjugates and bionanomaterial self-assembly (with relevance to PEGylated peptides used in therapeutic applications). The use of modified fragments of the amyloid beta peptide is especially interesting with respect to amyloid fibrillization and its control.

Journal Keywords: Hybrid Materials; Liquid Crystals; Peptides; Polymers

Subject Areas: Chemistry, Materials

Instruments: NONE-No attached Diamond beamline

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