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A [13]rotaxane assembled via a palladium molecular capsule

DOI: 10.1038/s41467-019-11635-6 DOI Help

Authors: Jesus Ferrando-soria (The University of Manchester; Universidad de Valencia) , Antonio Fernandez (The University of Manchester; Loughborough University) , Deepak Asthana (The University of Manchester) , Selina Nawaz (The University of Manchester) , IƱigo J. Vitorica-yrezabal (The University of Manchester) , George F. S. Whitehead (The University of Manchester) , Christopher A. Muryn (The University of Manchester) , Floriana Tuna (The University of Manchester) , Grigore A. Timco (The University of Manchester) , Neil D. Burton (The University of Manchester) , Richard E. P. Winpenny (The University of Manchester)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Nature Communications , VOL 10

State: Published (Approved)
Published: August 2019

Open Access Open Access

Abstract: Molecules that are the size of small proteins are difficult to make. The most frequently examined route is via self-assembly, and one particular approach involves molecular nanocapsules, where ligands are designed that will enforce the formation of specific polyhedra of metals within the core of the structure. Here we show that this approach can be combined with mechanically interlocking molecules to produce nanocapsules that are decorated on their exterior. This could be a general route to very large molecules, and is exemplified here by the synthesis and structural characterization of a [13]rotaxane, containing 150 metal centres. Small angle X-ray scattering combined with atomistic molecular dynamics simulations demonstrate the compound is intact in solution.

Journal Keywords: Interlocked molecules; Molecular capsules

Subject Areas: Chemistry

Instruments: I19-Small Molecule Single Crystal Diffraction


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