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Target highlights in CASP13: Experimental target structures through the eyes of their authors

DOI: 10.1002/prot.25805 DOI Help

Authors: Rosalba Lepore (BSC-CNS Barcelona Supercomputing Center) , Andriy Kryshtafovych (University of California) , Markus Alahuhta (National Renewable Energy Laboratory) , Harshul A. Veraszto (Max Planck Institute for Developmental Biology) , Yannick J. Bomble (National Renewable Energy Laboratory) , Joshua C. Bufton (Structural Genomic Consortium, University of Oxford; University of Bristol) , Alex N. Bullock (Structural Genomics Consortium, University of Oxford) , Cody Caba (University of Windsor) , Hongnan Cao (Rice University) , Owen R. Davies (Newcastle University) , Ambroise Desfosses (University of Auckland; Université Grenoble Alpes, CEA, CNRS) , Matthew Dunne (Institute of Food, Nutrition and Health, Zurich) , Krzysztof Fidelis (University of California) , Celia W. Goulding (University of California Irvine) , Manickam Gurusaran (Newcastle University) , Irina Gutsche (Université Grenoble Alpes, CEA, CNRS) , Christopher J. Harding (University of Birmingham) , Marcus D. Hartmann (Max Planck Institute for Developmental Biology) , Christopher S. Hayes (University of California, Santa Barbara) , Andrzej Joachimiak (Midwest Center for Structural Genomics; University of Chicago) , Petr G. Leiman (University of Texas Medical Branch) , Peter Loppnau (Structural Genomics Consortium, University of Toronto) , Andrew L. Lovering (University of Birmingham) , Vladimir V. Lunin (National Renewable Energy Laboratory) , Karolina Michalska (Midwest Center for Structural Genomics) , Ignacio Mir‐sanchis (The University of Chicago) , Alok Mitra (University of Auckland) , John Moult (University of Maryland) , George N. Phillips Jr (Rice University; University of Wisconsin) , Daniel Pinkas (Structural Genomics Consortium, University of Oxford) , Phoebe A. Rice (The University of Chicago) , Yufeng Tong (University of Windsor; Structural Genomics Consortium, University of Toronto) , Maya Topf (University College London) , Jonathan D. Walton (Michigan State University) , Torsten Schwede (Biozentrum University of Basel; SIB Swiss Institute of Bioinformatics)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Proteins: Structure, Function, And Bioinformatics , VOL 7

State: Published (Approved)
Published: September 2019
Diamond Proposal Number(s): 14692

Open Access Open Access

Abstract: The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP13 experiment.

Journal Keywords: CASP, protein structure prediction; cryo‐EM; X‐ray crystallography

Subject Areas: Biology and Bio-materials


Instruments: I02-Macromolecular Crystallography , I03-Macromolecular Crystallography , I04-1-Macromolecular Crystallography (fixed wavelength) , I04-Macromolecular Crystallography