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Differential adsorption of L- and D-lysine on achiral MFI zeolites as determined by synchrotron X-ray powder diffraction and thermogravimetric analysis

DOI: 10.1002/anie.201909352 DOI Help

Authors: Tianxiang Chen (The Hong Kong Polytechnic University) , Bolong Huang (The Hong Kong Polytechnic University) , Sarah Day (Diamond Light Source) , Chiu Chung Tang (Diamond Light Source) , Shik Chi Edman Tsang (University of Oxford) , Kwok-yin Wong (The Hong Kong Polytechnic University) , Tsz Woon Benedict Lo (The Hong Kong Polytechnic University)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Angewandte Chemie International Edition

State: Published (Approved)
Published: November 2019
Diamond Proposal Number(s): 23230

Abstract: We report the first crystallographic observation of stereospecific bindings of L‐ and D‐lysine in achiral MFI zeolites. The MFI structure has offered inherent geometric and internal confinement effects for the enantiomeric difference in L‐ and D‐lysine adsorption. Notable difference over the sorption properties has been observed by circular dichroism (CD) spectroscopy and thermogravimetric analysis (TGA). Distinct L‐ and D‐lysine adsorption behaviours on the H‐ZSM‐5 framework have been revealed by the Rietveld refinement of high‐resolution synchrotron X‐ray powder diffraction (SXRD) data and the density functional theory (DFT) calculation. Despite only demonstrated in L‐ and D‐lysine over MFI zeolites, the differential adsorption study sheds light towards the rational engineering of molecular interactions(s) with achiral microporous materials for chiral separation purposes.

Journal Keywords: chirality; Microporous materials; structural elucidation; synchrotron X-ray powder diffraction

Subject Areas: Biology and Bio-materials

Instruments: I11-High Resolution Powder Diffraction

Other Facilities: SPring-8