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Development of new biodegradable alloys for medical applications

DOI: 10.37904/metal.2019.745 DOI Help

Authors: Zuzana Molčanová (Institut of Materials Research, Slovak Academy of Sciences) , Beáta Balloková (Institut of Materials Research, Slovak Academy of Sciences) , Juraj Durisin (Technical University of Kosice) , Katarina Sulova (Institute of Materials Research, Slovak Academy of Sciences; Technical University of Košice) , Michaela Sulikova (Pavol Jozef Šafárik University in Košice) , Andrea Lachova (Pavol Jozef Šafárik University in Košice) , Maksym Lisnichuk (Pavol Jozef Šafárik University in Košice) , Milos Fejercak (Institut of Materials Research, Slovak Academy of Sciences; Pavol Jozef Šafárik University in Košice) , Slávka Martinková (Pavol Jozef Šafárik University in Košice) , Stefan Michalik (Diamond Light Source) , Karel Saksl (Institut of Materials Research, Slovak Academy of Sciences; Pavol Jozef Šafárik University in Košice)
Co-authored by industrial partner: No

Type: Conference Paper
Conference: 28th International Conference on Metallurgy and Materials
Peer Reviewed: Yes

State: Published (Approved)
Published: November 2019
Diamond Proposal Number(s): 20770

Open Access Open Access

Abstract: In surgery, besides the joint replacements that need permanent prosthesis implantation in the human body, there are many other clinical cases, such as bone fracture, cardiovascular diseases, in which the temporary implant materials are needed. The fixation or mechanical support are there temporarily needed during the healing process of the injured or pathological tissue, and after that, the implants accomplish their mission have no longer function in human body. In this case, biodegradable materials are the optimal choice as these materials do their job while healing and a new tissue forming occur and degrade in the human body thereafter. Amorphous alloys based on magnesium and calcium are nowadays a very perspective group of metallic glasses. We have developed composition series of completely new (not published) ternary Ca-Mg-Au biodegradable alloys with attractive properties in terms of possible future applications (density and elastic modulus comparable to human bones, wide supercooled liquid region etc.). Although the rate of their degradation in physiological solutions is still too fast, these ternary alloys will serve as precursors for design of future highly alloyed systems with tuned dissociation rate in human body.

Journal Keywords: Biodegradable, alloys, X-ray diffraction, nanoindentation, alloy dissolution

Subject Areas: Materials


Instruments: I15-1-X-ray Pair Distribution Function (XPDF)

Documents:
metal2019_molcanova_metal.pdf

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