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Synthesis of multilamellar walls vesicles polyelectrolyte surfactant complexes from pH-stimulated phase transition using microbial biosurfactants

DOI: 10.1016/j.jcis.2020.07.021 DOI Help

Authors: C. Seyrig (Sorbonne Université) , P. Le Griel (Sorbonne Université) , N. Cowieson (Diamond Light Source) , J. Perez (Synchrotron SOLEIL) , N. Baccile (Sorbonne Université)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Journal Of Colloid And Interface Science

State: Published (Approved)
Published: July 2020
Diamond Proposal Number(s): 23247

Abstract: Multilamellar wall vesicles (MLWV) are an interest class of polyelectrolyte-surfactant complexes (PESCs) for the wide applications ranging from house-care to biomedical products. If MLWV are generally obtained by a polyelectrolyte-driven vesicle agglutination under pseudo-equilibrium conditions, the resulting phase is often a mixture of more than one structure. In this work, we show that MLWV can be massively and reproductively prepared from a recently developed method involving a pH-stimulated phase transition from a complex coacervate phase (Co). We employ a biobased pH-sensitive microbial glucolipid biosurfactant in the presence of a natural, or synthetic, polyamine (chitosan, poly-L-Lysine, polyethylene imine, polyallylamine). In situ small angle X-ray scattering (SAXS) and cryogenic transmission electron microscopy (cryo-TEM) show a systematic isostructural and isodimensional transition from the Co to the MLWV phase, while optical microscopy under polarized light experiments and cryo-TEM reveal a massive, virtually quantitative, presence of MLWV. Finally, the multilamellar wall structure is not perturbed by filtration and sonication, two typical methods employed to control size distribution in vesicles. In summary, this work highlights a new, robust, non-equilibrium phase-change method to develop biobased multilamellar wall vesicles, promising soft colloids with applications in the field of personal care, cosmetics and pharmaceutics among many others.

Journal Keywords: Polyelectrolyte-Surfactant Complex; Complex coacervates; Biosurfactants; Polyelectrolytes; Multilamellar walls vesicles

Subject Areas: Chemistry, Biology and Bio-materials

Instruments: B21-High Throughput SAXS

Other Facilities: SOLEIL

Added On: 15/07/2020 10:29

Discipline Tags:

Molecular Complexes Physics Soft condensed matter physics Chemistry

Technical Tags:

Scattering Small Angle X-ray Scattering (SAXS)