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Diamond B23 CD imaging of thin films of chiral materials or achiral polymers coated with chiral molecules

DOI: 10.3390/sym12111847 DOI Help

Authors: Rohanah Hussain (Diamond Light Source) , Tamas Javorfi (Diamond Light Source) , Charlotte S. Hughes (Diamond Light Source) , Harini Sriram (Singapore Eye Research Institute) , Rajamani Lashminarayanan (Singapore Eye Research Institute) , Giuliano Siligardi (Diamond Light Source)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Symmetry , VOL 12

State: Published (Approved)
Published: November 2020
Diamond Proposal Number(s): 8893 , 14842 , 13518

Open Access Open Access

Abstract: The novel vertical sample chamber, developed at the B23 beamline for synchrotron radiation circular dichroism (SRCD), has enabled the Diamond User community to conduct different types of experiments from high throughput CD of protein and DNA folding using 96-well multiplates to CD imaging at high spatial resolution. Here, we present the application of CD imaging to large areas of achiral polymer PVA films doped with D-dopa to assess the chiral homogeneity of the film preparation with potential antimicrobial property. Synopsis: CDi application of Diamond B23 SRCD beamline.

Journal Keywords: synchrotron radiation circular dichroism (SRCD); vacuum-ultraviolet (VUV); CD imaging; film and suspension; homogeneity

Subject Areas: Biology and Bio-materials

Instruments: B23-Circular Dichroism