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ConPlot: Web-based application for the visualisation of protein contact maps integrated with other data

DOI: 10.1093/bioinformatics/btab049 DOI Help

Authors: Filomeno Sanchez Rodriguez (University of Liverpool; Diamond Light Source) , Shahram Mesdaghi (University of Liverpool) , Adam J Simpkin (University of Liverpool) , J. Javier Burgos-Marmol (University of Liverpool) , David L. Murphy (University of Liverpool) , Ville Uski (UKRI-STFC, Research Complex at Harwell) , Ronan Keegan (UKRI-STFC, Research Complex at Harwell) , Daniel J. Rigden (University of Liverpool)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Bioinformatics

State: Published (Approved)
Published: January 2021

Open Access Open Access

Abstract: Covariance-based predictions of residue contacts and inter-residue distances are an increasingly popular data type in protein bioinformatics. Here we present ConPlot, a web-based application for convenient display and analysis of contact maps and distograms. Integration of predicted contact data with other predictions is often required to facilitate inference of structural features. ConPlot can therefore use the empty space near the contact map diagonal to display multiple coloured tracks representing other sequence-based predictions. Popular file formats are natively read and bespoke data can also be flexibly displayed. This novel visualisation will enable easier interpretation of predicted contact maps.

Subject Areas: Information and Communication Technology, Biology and Bio-materials

Technical Areas:

Added On: 02/02/2021 09:40


Discipline Tags:

Data management / presentation Computing & software technologies Information & Communication Technologies Life Sciences & Biotech

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