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ConPlot: Web-based application for the visualisation of protein contact maps integrated with other data
DOI:
10.1093/bioinformatics/btab049
Authors:
Filomeno
Sanchez Rodriguez
(University of Liverpool; Diamond Light Source)
,
Shahram
Mesdaghi
(University of Liverpool)
,
Adam J
Simpkin
(University of Liverpool)
,
J. Javier
Burgos-Marmol
(University of Liverpool)
,
David L.
Murphy
(University of Liverpool)
,
Ville
Uski
(UKRI-STFC, Research Complex at Harwell)
,
Ronan
Keegan
(UKRI-STFC, Research Complex at Harwell)
,
Daniel J.
Rigden
(University of Liverpool)
Co-authored by industrial partner:
No
Type:
Journal Paper
Journal:
Bioinformatics
State:
Published (Approved)
Published:
January 2021

Abstract: Covariance-based predictions of residue contacts and inter-residue distances are an increasingly popular data type in protein bioinformatics. Here we present ConPlot, a web-based application for convenient display and analysis of contact maps and distograms. Integration of predicted contact data with other predictions is often required to facilitate inference of structural features. ConPlot can therefore use the empty space near the contact map diagonal to display multiple coloured tracks representing other sequence-based predictions. Popular file formats are natively read and bespoke data can also be flexibly displayed. This novel visualisation will enable easier interpretation of predicted contact maps.
Subject Areas:
Information and Communication Technology,
Biology and Bio-materials
Technical Areas:
Added On:
02/02/2021 09:40
Documents:
btab049.pdf
Discipline Tags:
Data management / presentation
Computing & software technologies
Information & Communication Technologies
Life Sciences & Biotech
Technical Tags: