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Collagen imaged by Coherent X-ray Diffraction: towards a complementary tool to conventional scanning SAXS

DOI: 10.1088/1742-6596/247/1/012004 DOI Help

Authors: Felisa Berenguer (London Centre of Nanotechnology) , Richard Bean (London Centre of Nanotechnology) , Catriona Mccallion (University College London) , Kris Wallace (University College London) , Laurent Bozec (University College London-Eastman Dental Institute) , Jennifer Hiller (Diamond Light Source) , Nicholas Terrill (Diamond Light Source) , Ian Robinson (Diamond Light Source)
Co-authored by industrial partner: No

Type: Conference Paper
Conference: SAS 2009
Peer Reviewed: No

State: Published (Approved)
Published: November 2010

Abstract: Third generation x-ray sources offer unique possibilities for exploiting coherence in the study of materials. New insights in the structure and dynamics of soft condensed matter and biological samples can be obtained by coherent x-ray diffraction (CXD). However, the experimental procedures for applying these methods to collagen tissues are still under development. We present here an investigation for the optimal procedure in order to obtain high quality CXD data from collagen tissues. Sample handling and preparation and adequate coherence defining apertures are among the more relevant factors to take into account. The impact of the results is also discussed, in particular in comparison with the information that can be extracted from conventional scanning small angle x-ray scattering (SAXS). Images of collagen tissues obtained by CXD reconstructions will give additional information about the local structure with higher resolution and will complement scanning SAXS images.

Subject Areas: Physics

Instruments: I22-Small angle scattering & Diffraction

Added On: 23/11/2010 08:32

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