Article Metrics


Online attention

Atomic-scale structural characterization of silver-doped phosphate-based glasses prepared by coacervation

DOI: 10.1021/acs.jpcc.1c00363 DOI Help

Authors: B. A. Kyffin (University of Surrey) , D. M. Pickup (University of Kent) , G. Mountjoy (University of Kent) , F. Foroutan (University of Surrey) , I. Abrahams (Queen Mary University of London) , D. Carta (University of Surrey)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: The Journal Of Physical Chemistry C , VOL 16

State: Published (Approved)
Published: May 2021
Diamond Proposal Number(s): 18595 , 18923 , 21525

Abstract: Phosphate-based glasses (PBGs) are traditionally prepared using the high-temperature melt-quenching (MQ) route or via the more recent sol–gel (SG) method that requires the use of organic solvents. The coacervation method represents an excellent inexpensive and green alternative to MQ and SG, being performed in aqueous solution and at room temperature. Coacervation is particularly applicable for the production of PBGs designed for biomedical applications because it allows for the inclusion of temperature-sensitive molecules and does not require the use of toxic solvents. Whereas the atomic structure of the MQ and SGPBGs is known, the atomic structure of those prepared via coacervation has yet to be investigated. In this study, a comprehensive advanced structural characterization has been performed on phosphate-based glasses in the system P2O5–CaO–Na2O–Ag2O (Ag2O mol % = 0, 1, 3, 5, 9, and 14) prepared via the coacervation method. Glasses within this system should find application as bioresorbable biomaterials thanks to their ability to release bioactive ions in a controlled manner. In particular, they possess antibacterial properties, inferred by the release of Ag+ over time. High-energy X-ray diffraction (HEXRD), 31P and 23Na solid-state magic-angle spinning nuclear magnetic resonance (MAS NMR), and X-ray absorption Spectroscopy (XAS) at the Ag K-edge were used to probe the atomic structure of the glasses after drying in vacuum and after calcination at 300 °C. The length of the polyphosphate chains in the solid state appears to be independent of silver concentration; however, significant degradation of these chains is seen after calcination at 300 °C. Atomic-scale characterisation results indicate that the structure of these glasses is akin to that of other silver-doped phosphate glasses prepared using the MQ and SG methods. This suggests that phosphate-based glasses prepared using milder and greener conditions may have similar chemical and physical properties such as solubility, biocompatibility, and antibacterial properties.

Journal Keywords: Anions; Ions; Extended X-ray absorption fine structure; Phosphates; Amorphous materials

Subject Areas: Chemistry, Materials

Instruments: B18-Core EXAFS , I15-1-X-ray Pair Distribution Function (XPDF)

Added On: 30/05/2021 20:51

Discipline Tags:

Biomaterials Physical Chemistry Chemistry Materials Science

Technical Tags:

Diffraction Spectroscopy X-ray Absorption Spectroscopy (XAS)