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Structural and mechanistic studies on Gamma-butyrobetaine hydroxylase. - Deleted

DOI: 10.1016/j.chembiol.2010.09.01 DOI Help

Authors: Ivanhoe Leung (University of Oxford) , Tobias Krojer (Oxford University SGC) , Grazyna Kochan (University of Oxford SGC) , Luc Henry (University of Oxford) , Frank Von Delft (University of Oxford) , Timothy Claridge (University of Oxford) , Udo Oppermann (University of Oxford) , Michael Mcdonough (Department of Chemistry, University of Oxford) , Christopher Schofield (University of Oxford)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Chemistry & Biology , VOL 17 , PAGES 1316-1324

State: Published (Approved)
Published: December 2010

Abstract: Crystal structure of gamma-butyrobetaine hydroxylase in complex with substrate and inhibitor, N-terminal Zn-binding domain involved in dimerization, The clinically used inhibitor, THP, is also a substrate for BBOX, BBOX catalyzed rearrangement reaction

Subject Areas: Chemistry


Instruments: I02-Macromolecular Crystallography

Added On: 05/04/2011 18:22

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