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Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor.

DOI: 10.1074/jbc.M110.193540 DOI Help
PMID: 21177872 PMID Help

Authors: Ming Yang (University of Oxford) , Wei Ge (University of Oxford) , Rasheduzzaman Chowdhury (University of Oxford) , Timothy Claridge (University of Oxford) , Holger Kramer (University of Oxford) , Bernhard Schmierer (University Of Oxford) , Michael A. Mcdonough (University of Oxford) , Lingzhi Gong (University of Oxford) , Benedikt Kessler (University of Oxford) , Peter Ratcliffe (University of Oxford) , Mathew Coleman (University of Oxford) , Christopher Schofield (University of Oxford)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Journal Of Biological Chemistry , VOL 286 (9) , PAGES 7648–7660

State: Published (Approved)
Published: March 2011

Abstract: Cytoskeleton, Post-translational Modification, Protein Stability, Protein Structure, Proteomics, Ankyrin Repeat Domain, AnkyrinR, Factor Inhibiting HIF, Hydroxylation, Hypoxia-inducible Factor

Journal Keywords: Ankyrins; Asparagine; Aspartic; Catalytic; Crystallography; Cytoskeleton; HEK293; Humans; Hydroxylation; Mixed; Peptide; Protein; Post-Translational; Protein; Tertiary; Recombinant; Repressor; Signal Transduction

Subject Areas: Chemistry

Instruments: I02-Macromolecular Crystallography