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Structure of the DNA-bound T-box domain of human TBX1, a transcription factor associated with the DiGeorge syndrome.

DOI: 10.1002/prot.23208 DOI Help
PMID: 22095455 PMID Help

Authors: Kamel El Omari (The Wellcome Trust Centre for Human Genetics, University of Oxford, U.K.) , Julie De Mesmaeker (The Wellcome Trust Centre for Human Genetics, University of Oxford, U.K.) , Dimple Karia (The Wellcome Trust Centre for Human Genetics, University of Oxford, U.K.) , Helen Ginn (The Wellcome Trust Centre for Human Genetics, University of Oxford, U.K.) , Shoumo Bhattacharya (The Wellcome Trust Centre for Human Genetics, University of Oxford, U.K.) , Erika J Mancini (The Wellcome Trust Centre for Human Genetics, University of Oxford, U.K.)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Proteins , VOL 80 (2) , PAGES 655 - 660,

State: Published (Approved)
Published: December 2011

Abstract: T-box proteins; transcription factors; protein-DNA interactions; crystal structure; DNA binding; Patient mutations

Subject Areas: Biology and Bio-materials, Medicine


Instruments: I24-Microfocus Macromolecular Crystallography

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