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Screening for cocrystals of succinic acid and 4-aminobenzoic acid

DOI: 10.1039/c2ce06325e DOI Help

Authors: Nizar Issa (University College London) , Sharmarke Mohamed (University College London) , Doris E. Braun (University College London) , Royston C. B. Copley (GlaxoSmithKline) , Derek A. Tocher (University College London) , Sarah L. Price (University College London) , Sarah A. Barnett (Diamond Light Source)
Co-authored by industrial partner: Yes

Type: Journal Paper
Journal: Crystengcomm , VOL 14 (7) , PAGES 2454-2464

State: Published (Approved)
Published: January 2012

Abstract: The ability of the pharmaceutically acceptable cocrystallising agents, succinic acid and 4-aminobenzoic acid, to form cocrystals with ten small organic molecules with hydrogen bonding acceptors but no donors, was investigated by grinding, hot-stage microscopy and solution based crystallisation experiments.

Subject Areas: Chemistry, Medicine

Instruments: I19-Small Molecule Single Crystal Diffraction

Added On: 25/11/2012 16:51

Discipline Tags:

Chemistry Organic Chemistry

Technical Tags:

Diffraction Single Crystal X-ray Diffraction (SXRD)