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Structural characterization of titanium-doped Bioglass using isotopic substitution neutron diffraction

DOI: 10.1039/c2cp43032k DOI Help

Authors: Richard Martin (University of Kent, U.K) , Robert M. Moss (University of Kent, U.K.) , Nilay Lakhkar (University College London) , Jonathan C. Knowles (University College London,, U.K.) , Gabriel J. Cuello (Institut Laue-Langevin, France) , Mark E. Smith (University of Warwick, U.K.) , John V. Hanna (University of Warwick, U.K.) , Bob Newport (University of Kent at Canterbury)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Physical Chemistry Chemical Physics , VOL 14 (45) , PAGES 15807-15815

State: Published (Approved)
Published: October 2012

Abstract: Melt quenched silicate glasses containing calcium, phosphorus and alkali metals have the ability to promote bone regeneration and to fuse to living bone. Of these glasses 45S5 Bioglasss is the most widely used being sold in over 35 countries as a bone graft product for medical and dental applications; particulate 45S5 is also incorporated into toothpastes to help remineralize the surface of teeth. Recently it has been suggested that adding titanium dioxide can increase the bioactivity of these materials. This work investigates the structural consequences of incorporating 4 mol% TiO2 into Bioglasss using isotopic substitution (of the Ti) applied to neutron di\ufb00raction and X-ray Absorption Near Edge Structure (XANES).

Subject Areas: Biology and Bio-materials

Instruments: I18-Microfocus Spectroscopy