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DNA interaction of CuII, NiII and ZnII functionalized Salphen complexes: studies by linear dichroism, gel electrophoresis and PCR

DOI: 10.1039/c3dt51090e DOI Help

Authors: Alessio Terenzi (University of Birmingham Edgbaston; Università di Palermo) , Cosimo Ducani (University of Birmingham Edgbaston) , Louise Male (University of Birmingham Edgbaston) , Giampaolo Barone (Università di Palermo) , Michael J. Hannon (University of Birmingham)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Dalton Transactions

State: Published (Approved)
Published: June 2013

Abstract: The interaction of of Salphen-type NiII, CuII and ZnII complexes with native DNA was investigated by exploiting linear dichroism experiments. The NiII complex behaves as a typical intercalator, binding strongly and stiffening and unwinding the DNA

Subject Areas: Biology and Bio-materials

Instruments: I19-Small Molecule Single Crystal Diffraction

Added On: 26/06/2013 15:22

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