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Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis

DOI: 10.1182/blood-2013-06-511733 DOI Help
PMID: 23869089 PMID Help

Authors: B. C. Lechtenberg , T. A. Murray-rust , D. J. D. Johnson , T. E. Adams , S. Krishnaswamy , R. M. Camire , James A. Huntington (University of Cambridge)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Blood

State: Published (Approved)
Published: July 2013

Abstract: The crystal structure of pro-pseutarin C reveals how the prothrombinase complex assembles and suggests a mechanism of prothrombin processing.

Journal Keywords: Binding; Blood; Crystallography ; X-Ray ; Elapid; Factor; Factor; Humans ; Models ; Molecular ; Mutation ; Protein; Tertiary ; Snake; Snakes ; Thromboplastin

Subject Areas: Biology and Bio-materials, Medicine


Instruments: I04-Macromolecular Crystallography

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