Selectivity and self-assembly in the control of a bacterial toxin by an antitoxic noncoding RNA pseudoknot

DOI: 10.1073/pnas.1216039110
PMID: 23267117

Authors: Francesca L. Short (University of Cambridge) , Xue Y. Pei (University of Cambridge) , Tim R. Blower (University of Cambridge) , Shue-Li Ong (University of Cambridge) , Peter C. Fineran (University of Cambridge) , Ben F. Luisi (University of Cambridge) , George P. C. Salmond (University of Cambridge)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Proceedings Of The National Academy Of Sciences , VOL 110 (3) , PAGES E241 - E249

State: Published (Approved)
Published: January 2013

Abstract: RNA inhibition | mRNA interferase | RNA-protein complex | abortive infection | plasmid stabilization

Journal Keywords: Antitoxins; Bacillus; Bacterial; Bacterial; Base; Crystallography; X-Ray; Models; Molecular; Mutagenesis; Nucleic; Pectobacterium; Plasmids; RNA; Bacterial; RNA; Untranslated; Ribonucleases; Sequence; Amino; Substrate Specificity

Diamond Keywords: Bacteria; Enzymes

Subject Areas: Biology and Bio-materials, Medicine


Instruments: I02-Macromolecular Crystallography

Added On: 30/09/2013 11:43

Discipline Tags:

Health & Wellbeing Structural biology Drug Discovery Life Sciences & Biotech

Technical Tags:

Diffraction Macromolecular Crystallography (MX)