Design of B23 Circular Dichroism beamline at Diamond Light Source

DOI: 10.1142/S1793617908000173

Authors: Rohanah Hussain (Diamond Light Source) , N Krumpa (STFC, Daresbury Laboratory, Diamond Light Source) , J Strachan (Diamond Light Source) , D Clarke (Diamond Light Source) , B Macdonald (Diamond Light Source) , D Reading (Diamond Light Source) , Ian Gillingham (Diamond Light Source) , A Price (Diamond Light Source) , M Smith (Diamond Light Source) , Guiliano Siligardi (Diamond Light Source) , T Cobb (Diamond Light Source) , Ulrich Wagner
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Advances In Synchrotron Radiation , VOL 1 (02) , PAGES 265-270

State: Published (Approved)
Published: December 2008

Abstract: Synchrotron circular dichroism (CD) is already a valuable technique for studies of protein folding, conformational changes and enzyme mechanisms, as well as secondary structure determination. Exciting new potential applications exist in protein folding, protein complex formation for Proteomics, and ligand/drug screening for Functional Genomics. With the 3 GeV synchrotron of Diamond Light Source we can collimate a very small size light beam (about 2 mm (H) × 1 mm (V)) with high photon flux (estimated 8 × 1013 (ph/s/0.1%bw) at 6 eV and 300 mA). The small beam size will enable the measurement of smaller sample volumes that previously has not been possible.

Journal Keywords: Synchrotron Radiation Circular Dichroism; Time-Resolved; Raman Optical Activity; Uhv

Subject Areas: Technique Development


Instruments: B23-Circular Dichroism