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Hierarchical tailoring of strut architecture to control permeability of additive manufactured titanium implants

DOI: 10.1016/j.msec.2013.05.050 DOI Help

Authors: Z. Zhang (Imperial College London, U.K.) , D. Jones (University of Liverpool, U.K.) , S. Yue (The University of Manchester, U.K.) , P. D. Lee (The University of Manchester, U.K.) , J.r. Jones (Imperial College London, U.K.) , C.j. Sutcliffe (Imperial College London, U.K.) , E. Jones (Stryker Orthopaedics, Ireland)
Co-authored by industrial partner: Yes

Type: Journal Paper
Journal: Materials Science And Engineering: C , VOL 33 (7) , PAGES 4055 - 4062

State: Published (Approved)
Published: October 2013
Diamond Proposal Number(s): 6108

Abstract: Porous titanium implants are a common choice for bone augmentation. Implants for spinal fusion and repair of non-union fractures must encourage blood flow after implantation so that there is sufficient cell migration, nutrient and growth factor transport to stimulate bone ingrowth. Additive manufacturing techniques allow a large number of pore network designs. This study investigates how the design factors offered by selective laser melting technique can be used to alter the implant architecture on multiple length scales to control and even tailor the flow. Permeability is a convenient parameter that characterises flow, correlating to structure openness (interconnectivity and pore window size), tortuosity and hence flow shear rates. Using experimentally validated computational simulations, we demonstrate how additive manufacturing can be used to tailor implant properties by controlling surface roughness at a microstructual level (microns), and by altering the strut ordering and density at a mesoscopic level (millimetre).

Journal Keywords: Titanium Porous Structures; Bone Ingrowth; Permeability; Additive Manufacturing; Selective Laser Melting

Subject Areas: Biology and Bio-materials


Instruments: I12-JEEP: Joint Engineering, Environmental and Processing

Added On: 27/10/2014 21:41

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