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X-ray phase contrast tomography by tracking near field speckle

DOI: 10.1038/srep08762 DOI Help
PMID: 25735237 PMID Help

Authors: Hongchang Wang (Diamond Light Source) , Sebastien Berujon (Diamond Light Source) , Julia Herzen (Institue of Materials Science) , Robert Atwood (Diamond Light Source) , David Laundy (Diamond Light Source) , Alexander Hipp (Helmholtz-Zentrum Geesthacht) , Kawal Sawhney (Diamond Light Source)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Scientific Reports , VOL 5

State: Published (Approved)
Published: March 2015

Open Access Open Access

Abstract: X-ray imaging techniques that capture variations in the x-ray phase can yield higher contrast images with lower x-ray dose than is possible with conventional absorption radiography. However, the extraction of phase information is often more difficult than the extraction of absorption information and requires a more sophisticated experimental arrangement. We here report a method for three-dimensional (3D) X-ray phase contrast computed tomography (CT) which gives quantitative volumetric information on the real part of the refractive index. The method is based on the recently developed X-ray speckle tracking technique in which the displacement of near field speckle is tracked using a digital image correlation algorithm. In addition to differential phase contrast projection images, the method allows the dark-field images to be simultaneously extracted. After reconstruction, compared to conventional absorption CT images, the 3D phase CT images show greatly enhanced contrast. This new imaging method has advantages compared to other X-ray imaging methods in simplicity of experimental arrangement, speed of measurement and relative insensitivity to beam movements. These features make the technique an attractive candidate for material imaging such as in-vivo imaging of biological systems containing soft tissue.

Subject Areas: Technique Development

Technical Areas: Optics