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Studies on the Reaction of Nitric Oxide with the Hypoxia-Inducible Factor Prolyl Hydroxylase Domain 2 (EGLN1)

DOI: 10.1016/j.jmb.2011.04.075 DOI Help
PMID: 21601578 PMID Help

Authors: Rasheduzzaman Chowdhury (Department of Chemistry, University of Oxford) , Emily Flashman (Department of Chemistry, University of Oxford) , Jasmin Mecinoviæ (Department of Chemistry, University of Oxford) , Holger B. Kramer (University of Oxford) , Benedikt M. Kessler (University of Oxford) , Yves M. Frapart (Université René Descartes) , Jean-luc Boucher (Université René Descartes) , Ian Clifton (The Department of Chemistry and Oxford Centre for Integrative Systems Biology, University of Oxford) , Michael Mcdonough (Department of Chemistry, University of Oxford) , Christopher J. Schofield (Department of Chemistry, University of Oxford)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Journal Of Molecular Biology , VOL 410 (2) , PAGES 268 - 279

State: Published (Approved)
Published: July 2011

Abstract: nitric oxide; 2-oxoglutarate; hypoxia-inducible factor; oxygen-dependent degradation domain; prolyl hydroxylase domain-containing enzyme

Journal Keywords: Anoxia; Crystallography; X-Ray; Humans; Hypoxia-Inducible; Hypoxia-Inducible; Molecular; Nitric; Procollagen-Proline; Protein; Tertiary; Spectrometry; Mass; Electrospray; Tandem Mass Spectrometry

Subject Areas: Biology and Bio-materials


Instruments: I04-Macromolecular Crystallography

Other Facilities: UK SRS Station 14.1

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