Engineering Homochiral Metal-Organic Frameworks by Spatially Separating 1D Chiral Metal-Peptide Ladders: Tuning the Pore Size for Enantioselective Adsorption

DOI: 10.1002/chem.201501315
PMID: 26033709

Authors: Kyriakos C. Stylianou (Institut Catala de Nanociencia i Nanotecnologia) , Laura Gómez (Universitat de Girona) , Inhar Imaz (Institut Catala de Nanotecnologia) , Cristobal Verdugo (CSIC - U.Granada) , Xavi Ribas (Universitat de Girona) , Daniel Maspoch (Institut Catala de Nanotecnologia)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Chemistry - A European Journal

State: Published (Approved)
Published: June 2015
Diamond Proposal Number(s): 8477

Abstract: The reaction of the chiral dipeptide glycyl-L(S)-glutamate with CoII ions produces chiral ladders that can be used as rigid 1D building units. Spatial separation of these building units with linkers of different lengths allows the engineering of homochiral porous MOFs with enhanced pore sizes, pore volumes, and surface areas. This strategy enables the synthesis of a family of isoreticular MOFs in which the pore size dictates the enantioselective adsorption of chiral molecules (in terms of their size and enantiomeric excess).

Journal Keywords: Chirality; Cobalt; Enantioselective Separation; Metal–Organic Frameworks; Peptides

Subject Areas: Chemistry


Instruments: I19-Small Molecule Single Crystal Diffraction