A 3D cellular context for the macromolecular world

DOI: 10.1038/nsmb.2897
PMID: 25289590

Authors: Ardan Patwardhan (European Molecular Biology Laboratory) , Alun Ashton (Diamond Light Source) , Robert Brandt (FEI Visualization Sciences Group) , Sarah Butcher (University of Helsinki) , Raffaella Carzaniga (Cancer Research UK London Research Institute) , Wah Chiu (Baylor College of Medicine) , Lucy Collinson (Cancer Research UK London Research Institute) , Pascal Doux (FEI Visualization Sciences Group) , Elizabeth Duke (Diamond Light Source) , Mark H. Ellisman (University of California, San Diego) , Erik Franken (FEI Electron Optics B.V) , Kay Grunewald (Wellcome Trust Centre for Human Genetics, University of Oxford) , Jean-Karim Heriche (European Molecular Biology Laboratory) , Abraham Koster (Leiden University Medical Center) , Werner Kühlbrandt (Max Planck Institute for Biophysics) , Ingvar Lagerstedt (Protein Data Bank in Europe) , Carolyn Larabell (University of California) , Catherine L. Lawson (Rutgers University) , Helen Saibil (ISMB, Birkbeck College) , Eduardo Sanz-García (European Molecular Biology Laboratory) , Sriram Subramaniam (National Cancer Institute (USA)) , Paul Verkade (University of Bristol) , Jason R Swedlow (University of Dundee) , Gerard J Kleywegt (European Molecular Biology Laboratory,)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Nature Structural & Molecular Biology , VOL 21 , PAGES 841 - 845

State: Published (Approved)
Published: October 2014

Abstract: We report the outcomes of the discussion initiated at the workshop entitled A 3D Cellular Context for the Macromolecular World and propose how data from emerging three-dimensional (3D) cellular imaging techniques—such as electron tomography, 3D scanning electron microscopy and soft X-ray tomography—should be archived, curated, validated and disseminated, to enable their interpretation and reuse by the biomedical community.

Journal Keywords: Computational biology and bioinformatics; Cryoelectron microscopy; Cryoelectron tomography; X-ray crystallography

Subject Areas: Biology and Bio-materials


Technical Areas:

Added On: 19/02/2016 12:08

Documents:
nsmb.2897.pdf

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Structural biology Life Sciences & Biotech

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