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Synchrotron FTIR mapping of mineralization in a microfluidic device

DOI: 10.1039/C6LC01393G DOI Help

Authors: Shunbo Li (University of Leeds) , Johannes Ihli (University of Leeds) , William Marchant (University of Leeds) , Muling Zeng (University of Leeds) , Li Chen (University of Leeds) , Katia Wehbe (Diamond Light Source) , Gianfelice Cinque (Diamond Light Source) , Oscar Cespedes (University of Leeds) , Nikil Kapur (University of Leeds) , Fiona Meldrum (University of Leeds)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Lab On A Chip

State: Published (Approved)
Published: March 2017
Diamond Proposal Number(s): 12717

Abstract: Fourier transform infrared micro-spectroscopy provides an effective means of performing rapid, non-destructive, and label-free analysis of specimens according to their vibrational modes. However, as water absorbs very strongly in the infrared region, analysis of aqueous solutions in transmission mode can suffer from problems with signal saturation. We here describe the fabrication of a novel microfluidic device that overcomes this problem. Devices with channel depths of just 3 ┬Ám were constructed from calcium fluoride using photolithography and hot embossing bonding, where calcium fluoride was selected due to its transparency in the IR region. The utility of this device was then demonstrated by employing it to follow the precipitation pathways of calcium sulfate and calcium carbonate using synchrotron FTIR micro-spectroscopy. Importantly, due to the high brightness provided by synchrotron radiation, and the fact that the reacting ions (HCO3- , CO32- and SO42-) and the different mineral polymorphs all have finger print spectra in the measured IR range, this method can be used to acquire time-resolved, hyperspectral maps of the mineral particles formed within the sample cell, and then study the interaction and evolution of particles. The data provide new insight into the formation pathway of a population of crystals in confined volumes, and demonstrate that this in situ, real-time detection system provides a powerful tool for studying crystallization processes.

Subject Areas: Technique Development, Chemistry, Physics

Instruments: B22-Multimode InfraRed imaging And Microspectroscopy

Added On: 04/04/2017 10:46

Discipline Tags:

Physics Physical Chemistry Technique Development - Chemistry Technique Development - Physics Chemistry

Technical Tags:

Spectroscopy Infrared Spectroscopy Synchtron-based Fourier Transform Infrared Spectroscopy (SR-FTIR)