Self-Assembled 2D Free-Standing Janus Nanosheets with Single-Layer Thickness

DOI: 10.1021/jacs.7b06591

Authors: Yiyang Lin (Imperial College London) , Michael R. Thomas (Imperial College London) , Amy Gelmi (Imperial College London) , Vincent Leonardo (Imperial College London) , E. Thomas Pashuck (Imperial College London) , Stephanie A. Maynard (Imperial College London) , Ye Wang (Imperial College London) , Molly M. Stevens (Imperial College London)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Journal Of The American Chemical Society

State: Published (Approved)
Published: September 2017
Diamond Proposal Number(s): 14792

Abstract: We report the thermodynamically controlled growth of solution-processable and free-standing nanosheets via peptide assembly in two dimensions. By taking advantage of self-sorting between peptide β-strands and hydrocarbon chains, we have demonstrated the formation of Janus 2D structures with single-layer thickness, which enable a predetermined surface heterofunctionalization. A controlled 2D-to-1D morphological transition was achieved by subtly adjusting the intermolecular forces. These nanosheets provide an ideal substrate for the engineering of guest components (e.g., proteins and nanoparticles), where enhanced enzyme activity was observed. We anticipate that sequence-specific programmed peptides will offer promise as design elements for 2D assemblies with face-selective functionalization.

Subject Areas: Biology and Bio-materials, Chemistry


Instruments: I22-Small angle scattering & Diffraction

Documents:
j454545acs.pdf