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Delivering selective and cell-active inhibitors of V804M mutant RET kinase through structure-guided drug discovery

DOI: 10.1158/1538-7445.AM2017-3236 DOI Help

Authors: Allan M. Jordan (Cancer Research UK Manchester Inst.) , Rebecca Newton (Cancer Research UK Manchester Inst.) , Bohdan Waszkowycz (Cancer Research UK Manchester Inst.) , Richard Bayliss , Habiba Begum (Cancer Research UK Manchester Inst.) , Daniel Burschowsky , Aude Echalier (Structural Genomics Consortium (SGC), University of Oxford) , Samantha Hitchin (Cancer Research UK Manchester Inst.) , Colin Hutton (Cancer Research UK Manchester Inst.) , Shaun Johns (Cancer Research UK Manchester Inst.) , Stuart Jones (Cancer Research UK Manchester Inst.) , Li-ying Lin (University of Leicester) , Mark Richards (University of Leeds) , Chitra Seewooruthun , Alex Stowell (Cancer Research UK Manchester Inst.) , Ian Waddell (Cancer Research UK Manchester Inst.) , Mandy Watson (Cancer Research UK Manchester Inst.) , Donald Ogilvie (Cancer Research UK Manchester Inst.)
Co-authored by industrial partner: No

Type: Conference Paper
Conference: American Association for Cancer Research Annual Meeting 2017
Peer Reviewed: No

State: Published (Approved)
Published: July 2017
Diamond Proposal Number(s): 10369 , 14692

Subject Areas: Medicine


Instruments: I04-1-Macromolecular Crystallography (fixed wavelength) , I04-Macromolecular Crystallography

Added On: 27/09/2017 14:31

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