Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016)

DOI: 10.1002/prot.25392

Authors: Andriy Kryshtafovych (University of California) , Reinhard Albrecht (Max Planck Institute for Developmental Biology) , Arnaud Basle (University of Newcastle Upon Tyne) , Pedro Bule (CIISA-Faculdade de Medicina Veterinária, Universidade de Lisboa) , Alessandro T. Caputo (Oxford Glycobiology Institute, University of Oxford) , Ana Luisa Carvalho (UCIBIO, REQUIMTE) , Kinlin L. Chao (Institute for Bioscience and Biotechnology Research, University of Maryland) , Ron Diskin (Weizmann Institute of Science) , Krzysztof Fidelis (University of California) , Carlos M. G. A. Fontes (Universidade de Lisboa) , Folmer Fredslund (University of Copenhagen) , Harry J. Gilbert (University of Newcastle) , Celia W. Goulding (University of California Irvine) , Marcus D. Hartmann (Max Planck Institute for Developmental Biology) , Christopher S. Hayes (University of California) , Osnat Herzberg (University of Maryland) , Johan C. Hill (University of Oxford) , Andrzej Joachimiak (Argonne National Laboratory; University of Chicago) , Gert-wieland Kohring (Saarland University) , Roman I. Koning (Leiden University; Leiden University Medical Center) , Leila Lo Leggio (University of Copenhagen) , Marco Mangiagalli (University of Milano‐Bicocca) , Karolina Michalska (Argonne National Laboratory) , John Moult (University of Maryland; Institute for Bioscience and Biotechnology Research) , Shabir Najmudin (CIISA ‐ Faculdade de Medicina Veterinária, Universidade de Lisboa) , Marco Nardini (University of Milano) , Valentina Nardone (University of Milano) , Didier Ndeh (University of Newcastle) , Thanh-hong Nguyen (Nacional de Biotecnologia (CSIC)) , Guido Pintacuda (Université de Lyon) , Sandra Postel (University of Maryland School of Medicine) , Mark J. Van Raaij (Centro Nacional de Biotecnologia (CSIC)) , Pietro Roversi (University of Oxford; University of Leicester) , Amir Shimon (Weizmann Institute of Science) , Abhimanyu K. Singh (University of Kent) , Eric J. Sundberg (University of Maryland School of Medicine) , Kaspars Tars (Latvian Biomedical Research and Study Center) , Nicole Zitzmann (Oxford Glycobiology Institute, University of Oxford) , Torsten Schwede (Biozentrum/SIB Swiss Institute of Bioinformatics)
Co-authored by industrial partner: No

Type: Journal Paper
Journal: Proteins: Structure, Function, And Bioinformatics , VOL 86 , PAGES 27 - 50

State: Published (Approved)
Published: March 2018

Abstract: The functional and biological significance of the selected CASP12 targets are described by the authors of the structures. The crystallographers discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP12 experiment.

Subject Areas: Biology and Bio-materials


Technical Areas: